A. Product Introduction

In Lab Medical EXOBIO PLUS represents the pinnacle of modern cosmeceutical innovation. As the global aesthetic market shifts toward regenerative medicine, EXOBIO PLUS emerges as a definitive "Multi-Action Pro-Age Revitalizer." The formulation concept is built on the synergy between advanced exosome technology and a high-standard vitalizing complex, designed to "re-awaken" the skin’s natural regenerative capacity.

This professional-grade system is strategically positioned for the elite aesthetic and medical-cosmetic market. It is intended exclusively for professional use, catering to dermatologists and aesthetic clinicians who utilize advanced delivery systems such as the Inlabpen (microneedling) or electroporation. By addressing the skin's health at a cellular level, EXOBIO PLUS goes beyond traditional topical care to provide a solution for visible imperfections, loss of density, and environmental damage.

B. Active Ingredients

The efficacy of EXOBIO PLUS is rooted in its high exosome concentration and the inclusion of standardized bio-actives that work in metabolic harmony:

1. EXO-VITALIZE Technology (2.8 x 10¹³ Exosomes/ml)

Exosomes are nanometer-sized extracellular vesicles that act as the skin's primary communication system. In EXOBIO PLUS, these vesicles deliver vital signals to fibroblasts and keratinocytes. This high-concentration activator induces a "transforming effect" on cellular functions, promoting a conducive environment for rapid tissue repair and the homogenization of the skin’s appearance.

2. Cobiogenol: The Epigenetic Energy Source

Cobiogenol is a functional ingredient consisting of purified marine glycogen. In cosmetic science, glycogen is recognized as the primary fuel for cellular activities. Cobiogenol specifically helps reduce biological alterations resulting from Electromagnetic Radiation (REM) and blue light exposure. By restoring the energy levels of the epidermis, it facilitates the continuous restoration of the skin barrier.

3. Stabilized Vitamin C & DNA Protection

Unlike standard L-ascorbic acid, the stabilized Vitamin C used in this system is engineered for deep penetration. It serves as a scavenger for free radicals, reversing auto-oxidation and protecting cellular DNA. This is critical for preventing photo-aging and reducing the appearance of age spots while providing the necessary cofactors for neo-collagenogenesis.

4. Bio-mimetic Peptides: Growth Factor Agonists

These synthetic peptides mimic the action of natural growth factors (GF). They bind to specific receptors on the cell surface to regulate the expression of the Extracellular Matrix (ECM). This process ensures that the production of collagen, elastin, and laminin is optimized, leading to a visible improvement in skin elasticity and structural firmness.

C. Indications

EXOBIO PLUS is indicated for intensive professional treatments targeting the following aesthetic discontinuities:

• Deep Structural Aging: Recommended for skin showing significant loss of density, deep wrinkles, and sagging.
• Irregular Skin Texture: Effectively addresses surface irregularities, enlarged pores, and post-inflammatory marks.
• Environmental and Digital Stress: Specifically indicated for skin exposed to high levels of pollution, UV radiation, and blue light (HEV).
• Luminosity and Tone Recovery: Ideal for dull, sallow complexions requiring a "shock treatment" of radiance and revitalization.
• Professional Application Context: This solution is strictly for topical professional application. It is highly compatible with Microneedling (Inlabpen), radiofrequency, and ultrasound technologies, which enhance the bioavailability of the exosomes within the dermal layers.
• Regulatory Status: Fully notified under CPNP Reference: 4668511, meeting the most stringent European safety and quality standards for international marketing.

D. Technical Specifications

• Formulation Type: Dual-phase sterile system (Exosome Activator + Vitalizing Complex).
• Texture & Aspect: Fluid, non-greasy liquids designed for rapid absorption.
• Primary Packaging: Amber glass vials (5 ml / 0.17 fl.oz) to protect the sensitive peptides and exosomal vesicles from light-induced degradation.
• Presentation: Professional clinical box containing 8 vials (8 x 5ml).
• Storage & Conservation: Store in a cool, dry place (<35 C). Protect from direct sunlight and heat to maintain the integrity of the bio-vesicles.
• Shelf Life: 12 months after opening (12M PAO). The product must be used immediately after the vial is opened to ensure sterile integrity.